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Job ID :
India - Bangalore
Job Title: Scientist I, Protein Biology
Job Location: India, Bangalore
ThermoFisher Scientific Inc. is the world leader in serving science, with revenues of more than $20 billion and approximately 70,000 employees globally. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics, deliver medicines to market and increase laboratory productivity.
Through our premier brands – ThermoFisher Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive services.
About Team: Protein Biology
The Protein Biology team in involved in large-scale function validation of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include data processing and mining of protein biology; Western blots with state-of-art tools, High throughput and high-resolution Immuno-fluorescence imaging, and access to tools such as ChIP (Chromatin Immunoprecipitation), Gene-silencing to provide advance application tags to our antibody portfolio. The goal of the program is advanced product validation, creation of product information to promote research use.
Role & Responsibilities
Purpose: - To perform Antibody and target biology validation, using state-of-art using cell and molecular biology methods for creating data sets to enable high quality products. To role requires candidate to be rigorous in scientific experimental planning and execution. Fluency in verbal and written communication of results in the work-place is highly desired.
Detailed curation of protein biology and target biology that include protein expression, modification and sub-cellular localization, guided by researching scientific publication and mining data repositories.
Perform at high level of proficiency in the use of cell and molecular biology methods. Expertise in protein analysis use of gel-electrophoresis, SDS-PAGE, Cell lysate preparation/western blotting and or other proteomic tools.
Cellular and tissue imaging by immunofluorescence, immunohistochemistry/tissue processing and/or other biological imaging methods
Recording results into data sheets and/or electronic note books is a job requirement. Familiarity with use of spreadsheets, retrieval of data from web/data repositories and use word and image processing software highly desired
Delivery of high quality results, attention to details and schedules to support program objectives
Education & Experience levels:
Applicants should have Masters with 1+ years’ experience in the area of cell biology, molecular biology, immunology, biotechnology/biochemistry
Nature of experience:
Project of work experience in support of relevant skills such as publications, project reports or thesis work
Familiar with working in a cell and molecular biology lab, with experience in handling protein expression, protein characterization or immunoassays.
Theoretical and practical understanding of ELISA, cell-lysate preparation, SDS-PAGE and western-blotting. Working knowledge of basic biochemical, cellular & molecular biologic techniques for protein characterization
Foundational knowledge in microscopy. Highly desired to have experience in cellular imaging or tissue imaging. Candidate should have a thorough understanding of and experience with immunostaining, cellular physiology, histology/pathology and fluorescence/ confocal microscopy techniques in mammalian cell and tissue systems
Sound theoretical understanding of protein structure, function and biology. Should be able to analyze biological pathway data and has a desire to mine data repositories for current information
Capable to creating robust experimental plan and can work within cross-functional teams with ability to perform technical trouble-shooting
Successful candidate will have clear functional communication at work-place and be open to learn and solve new challenges.
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